Magnetic nanoparticle detectors for medical diagnostics

Electronic biosensors have the potential to provide a revolution in healthcare by enabling sophisticated yet economical medical diagnostics at the point of care. This project’s aim is to develop smaller, faster magnetic nanoparticle sensors for application in magnetic biosensing techniques.

From remote communities to emergency departments in major hospitals, rapid medical diagnostics can be critical. Sophisticated biosensors aim to facilitate diagnostics at the point of care, whether it be a patient’s bedside or out in the field. In magnetic biosensing techniques, chemically modified magnetic particles act as nano-scale “tags” to label disease markers in biological samples. These particles can be thought of as tiny magnets and can be detected electronically using miniaturised magnetic field sensors, thereby providing information about the presence of particular disease markers in (eg.) a blood or urine sample. These magnetic biosensing techniques are highly promising candidates for use in future medical diagnostics tools, being not only robust and sensitive, but also compatible with a wide range of biological media.

This project combines nano-electronic and nano-magnetic device fabrication, measurement and simulation in an effort to develop and optimise new techniques for electronic nanoparticle detection. By exploiting recent advances in our understanding of magnetic nanostructures, Professor Metaxas aims to facilitate the development of faster, smaller magnetic bio-label sensors for use in future generations of electronic diagnostic tools, in turn bringing together researchers and research students from UWA, France, Singapore and the UK.

Collaborator/s

  • Dr Vincent Cros, Unité Mixte de Physique CNRS/Thales and Université Paris-Sud
  • Dr Abdelmadjid Anane, Unité Mixte de Physique CNRS/Thales and Université Paris-Sud
  • Professor Adekunle Adeyeye, National University of Singapore
  • Professor Hans Fangohr, University of Southampton